fbpx

Better understanding of diabetic retinopathy treatment

Lowering blood glucose levels is not enough when treating diabetic retinopathy, according to German researchers.

 

Numerous proteins and molecules are involved in the process of optical signal transduction from the retina to the brain. Diabetic retinal damage leads to impaired function of these proteins. Scientists at Helmholtz Zentrum München (HMGU), in Munich, compared the concentrations of proteins in the retinas of non-diabetic mice, of mice with type 2 diabetes without treatment and of type 2 diabetic mice that were treated with the drug metformin. This treatment lowers blood glucose levels.

 

In total, 98 proteins were less abundant in the diabetic animals. About half of the proteins were normalized by treatment with metformin, while the others remained insufficient. Among these was the protein VGLUT1, which is essential for visual signal transduction.

 

“Our results show that normalized blood glucose levels alone are not sufficient to fully treat diabetic retinopathy,” said Dr. Alice Ly, a lead author of the study. “In further studies we want to examine how different combination therapies affect the retinal proteins, in order to achieve a better understanding of the causes and treatment of this diabetes complication.”

Source:

http://www.sciencedaily.com/releases/2013/10/131007094243.htm

Featured Posts

March-April Optik 2025 Sustainability in Sight article

Sustainability in Sight: Green Frames, Lenses, and Best Practices

From Italy to Canada, discover the brands making sustainability more than a trend in eyewear—from renewable acetate to zero-waste contact lens programs.

Learn More
Voila March-April Optik 2025 AYA CETANGI

Buffalo Spirit Meets Modern Vision: AYA Optical x Lakota Artist Yellowhawk

AYA Optical proudly introduces Cetangi, the latest eyewear style featuring Jim Yellowhawk’s White Buffalo design.

Read more
EssilorLuxottica

New Six-Year Data Confirms Long-Term Efficacy of Essilor Stellest Lenses in Slowing Myopia Progression

New six-year clinical data confirms the long-term efficacy of Essilor Stellest lenses in slowing myopia progression and axial elongation in children and teens, reinforcing their role in myopia management.

Read more
Eye On the Industry podcast EOTI

Introducing Eye on the Industry: The Premier Podcast for Eyecare Professionals

Eye on the Industry, a groundbreaking podcast for eyecare professionals, is officially launching with a mission to provide invaluable insights into leadership, industry trends, and all things optical.

Read more
Nikon Optical Canada logo

Nikon Optical Canada Launches New Sun Lens Offer Including New Tint Colors for Stylish Protection

Nikon Optical Canada launches its new sun lens collection, including trendy SunStyle tints, polarized lenses, and SeeSun Mirror options—available in a wide range of Nikon designs starting April 15, 2025.

Read more
March-April Optik 2025 Sustainability in Sight article

Sustainability in Sight: Green Frames, Lenses, and Best Practices

From Italy to Canada, discover the brands making sustainability more than a trend in eyewear—from renewable acetate to zero-waste contact lens programs.

Learn More
Voila March-April Optik 2025 AYA CETANGI

Buffalo Spirit Meets Modern Vision: AYA Optical x Lakota Artist Yellowhawk

AYA Optical proudly introduces Cetangi, the latest eyewear style featuring Jim Yellowhawk’s White Buffalo design.

Read More
EssilorLuxottica

New Six-Year Data Confirms Long-Term Efficacy of Essilor Stellest Lenses in Slowing Myopia Progression

New six-year clinical data confirms the long-term efficacy of Essilor Stellest lenses in slowing myopia progression and axial elongation in children and teens, reinforcing their role in myopia management.

Read More
Eye On the Industry podcast EOTI

Introducing Eye on the Industry: The Premier Podcast for Eyecare Professionals

Eye on the Industry, a groundbreaking podcast for eyecare professionals, is officially launching with a mission to provide invaluable insights into leadership, industry trends, and all things optical.

Read More
Nikon Optical Canada logo

Nikon Optical Canada Launches New Sun Lens Offer Including New Tint Colors for Stylish Protection

Nikon Optical Canada launches its new sun lens collection, including trendy SunStyle tints, polarized lenses, and SeeSun Mirror options—available in a wide range of Nikon designs starting April 15, 2025.

Read More
March-April Optik 2025 Sustainability in Sight article

Sustainability in Sight: Green Frames, Lenses, and Best Practices

From Italy to Canada, discover the brands making sustainability more than a trend in eyewear—from renewable acetate to zero-waste contact lens programs.

Learn More
Voila March-April Optik 2025 AYA CETANGI

Buffalo Spirit Meets Modern Vision: AYA Optical x Lakota Artist Yellowhawk

AYA Optical proudly introduces Cetangi, the latest eyewear style featuring Jim Yellowhawk’s White Buffalo design.

Read more
EssilorLuxottica

New Six-Year Data Confirms Long-Term Efficacy of Essilor Stellest Lenses in Slowing Myopia Progression

New six-year clinical data confirms the long-term efficacy of Essilor Stellest lenses in slowing myopia progression and axial elongation in children and teens, reinforcing their role in myopia management.

Read more
Eye On the Industry podcast EOTI

Introducing Eye on the Industry: The Premier Podcast for Eyecare Professionals

Eye on the Industry, a groundbreaking podcast for eyecare professionals, is officially launching with a mission to provide invaluable insights into leadership, industry trends, and all things optical.

Read more
Nikon Optical Canada logo

Nikon Optical Canada Launches New Sun Lens Offer Including New Tint Colors for Stylish Protection

Nikon Optical Canada launches its new sun lens collection, including trendy SunStyle tints, polarized lenses, and SeeSun Mirror options—available in a wide range of Nikon designs starting April 15, 2025.

Read more
March-April Optik 2025 Sustainability in Sight article

Sustainability in Sight: Green Frames, Lenses, and Best Practices

From Italy to Canada, discover the brands making sustainability more than a trend in eyewear—from renewable acetate to zero-waste contact lens programs.

Learn More
Voila March-April Optik 2025 AYA CETANGI

Buffalo Spirit Meets Modern Vision: AYA Optical x Lakota Artist Yellowhawk

AYA Optical proudly introduces Cetangi, the latest eyewear style featuring Jim Yellowhawk’s White Buffalo design.

Read more
EssilorLuxottica

New Six-Year Data Confirms Long-Term Efficacy of Essilor Stellest Lenses in Slowing Myopia Progression

New six-year clinical data confirms the long-term efficacy of Essilor Stellest lenses in slowing myopia progression and axial elongation in children and teens, reinforcing their role in myopia management.

Read more
Eye On the Industry podcast EOTI

Introducing Eye on the Industry: The Premier Podcast for Eyecare Professionals

Eye on the Industry, a groundbreaking podcast for eyecare professionals, is officially launching with a mission to provide invaluable insights into leadership, industry trends, and all things optical.

Read more
Nikon Optical Canada logo

Nikon Optical Canada Launches New Sun Lens Offer Including New Tint Colors for Stylish Protection

Nikon Optical Canada launches its new sun lens collection, including trendy SunStyle tints, polarized lenses, and SeeSun Mirror options—available in a wide range of Nikon designs starting April 15, 2025.

Read more