UBirmingham Develops Eyedrops to Replace Injections for AMD Treatment

A team of researchers at the UK’s University of Birmingham led by biochemist Dr. Felicity de Cogan have developed eye drops which are capable of delivering drugs to the relevant area of the eye.

Eye drops would be safer and easier to administer than injections currently used, which run the risk of tearing and infection within the eye that could result in blindness.

The eyedrop formula uses cell-penetrating peptides (CPP), short chained molecules which allow the “cargo,” in this case the anti-AMD drugs bevacizumab and ranibizumab, to get taken into cells and delivered to the eye’s posterior chamber.

The eye drops delivered clinically relevant amounts of bevacizumab and ranibizumab to the posterior chamber of rat’s eyes within six minutes during in vivo tests. Similar results were obtained testing with porcine eyes.

“The CPP-drug has the potential to have a significant impact on the treatment of AMD by revolutionising drug-delivery options. Efficacious self-administered drug application by eye drop would lead to a significant reduction in adverse outcomes and health care costs compared with current treatments,” says the study’s lead author Dr. de Cogan.

Cell-penetrating peptides have applications for other ocular diseases as well, according to Dr. de Cogan.

 

Read the the full article HERE.

 

Featured Posts

Eye Recommend Acquires Digital ECP

Doctors Eye Care Co-Op Ltd. (operating as Eye Recommend) and Digital ECP Inc. announced that Eye Recommend has acquired Digital ECP Inc. effective September 30, 2022.

Learn More

Vintage is Back with ic! berlin’s Geoffrey

Introduced in the Acetate Hybrid Collection launched in March from ic! berlin, the Geoffrey frame reintroduces the vintage square style we all love with bold new colourways.

Read more

MIDO 2023: Visitor Registration Now Open

Starting now, show goers can reserve their spot at the 2023 edition of MIDO

Read more

FYidoctors Named Among Canada’s Top Growing Companies in Latest Report on Business Ranking

Diversified healthcare organization has grown to include 375 clinics across Canada

Read more

Bausch + Lomb Will Present Scientific Data and Analyses During World Cornea Congress

One Podium and Two Poster Presentations Will Highlight Pre-Clinical and Clinical Data for Investigational Treatment NOV03, as well as Data from Company’s Unique ARMOR Surveillance Study

Read more

Eye Recommend Acquires Digital ECP

Doctors Eye Care Co-Op Ltd. (operating as Eye Recommend) and Digital ECP Inc. announced that Eye Recommend has acquired Digital ECP Inc. effective September 30, 2022.

Learn More

Vintage is Back with ic! berlin’s Geoffrey

Introduced in the Acetate Hybrid Collection launched in March from ic! berlin, the Geoffrey frame reintroduces the vintage square style we all love with bold new colourways.

Read More

MIDO 2023: Visitor Registration Now Open

Starting now, show goers can reserve their spot at the 2023 edition of MIDO

Read More

FYidoctors Named Among Canada’s Top Growing Companies in Latest Report on Business Ranking

Diversified healthcare organization has grown to include 375 clinics across Canada

Read More

Bausch + Lomb Will Present Scientific Data and Analyses During World Cornea Congress

One Podium and Two Poster Presentations Will Highlight Pre-Clinical and Clinical Data for Investigational Treatment NOV03, as well as Data from Company’s Unique ARMOR Surveillance Study

Read More

Eye Recommend Acquires Digital ECP

Doctors Eye Care Co-Op Ltd. (operating as Eye Recommend) and Digital ECP Inc. announced that Eye Recommend has acquired Digital ECP Inc. effective September 30, 2022.

Learn More

Vintage is Back with ic! berlin’s Geoffrey

Introduced in the Acetate Hybrid Collection launched in March from ic! berlin, the Geoffrey frame reintroduces the vintage square style we all love with bold new colourways.

Read more

MIDO 2023: Visitor Registration Now Open

Starting now, show goers can reserve their spot at the 2023 edition of MIDO

Read more

FYidoctors Named Among Canada’s Top Growing Companies in Latest Report on Business Ranking

Diversified healthcare organization has grown to include 375 clinics across Canada

Read more

Bausch + Lomb Will Present Scientific Data and Analyses During World Cornea Congress

One Podium and Two Poster Presentations Will Highlight Pre-Clinical and Clinical Data for Investigational Treatment NOV03, as well as Data from Company’s Unique ARMOR Surveillance Study

Read more

Eye Recommend Acquires Digital ECP

Doctors Eye Care Co-Op Ltd. (operating as Eye Recommend) and Digital ECP Inc. announced that Eye Recommend has acquired Digital ECP Inc. effective September 30, 2022.

Learn More

Vintage is Back with ic! berlin’s Geoffrey

Introduced in the Acetate Hybrid Collection launched in March from ic! berlin, the Geoffrey frame reintroduces the vintage square style we all love with bold new colourways.

Read more

MIDO 2023: Visitor Registration Now Open

Starting now, show goers can reserve their spot at the 2023 edition of MIDO

Read more

FYidoctors Named Among Canada’s Top Growing Companies in Latest Report on Business Ranking

Diversified healthcare organization has grown to include 375 clinics across Canada

Read more

Bausch + Lomb Will Present Scientific Data and Analyses During World Cornea Congress

One Podium and Two Poster Presentations Will Highlight Pre-Clinical and Clinical Data for Investigational Treatment NOV03, as well as Data from Company’s Unique ARMOR Surveillance Study

Read more