CRISPR: Making the Cut to Restore Vision

CRISPR (also known as CRISPR-Cas9) is a gene editing technique that allows scientists to cut DNA very precisely. It’s like a pair of molecular scissors that can be used to cut mutations out, or add new pieces of DNA into a gene. The importance of this tool was
highlighted in October 2020 when Dr. Emmanuelle Charpentier (Max Planck, Berlin) and Dr. Jennifer Doudna (University of California, Berkeley) were awarded the 2020 Nobel prize in Chemistry for this discovery.

CRISPR is actually a natural part of a bacteria’s immune system. It was discovered by Dr. Charpentier in 2011 and soon after, working with Dr. Doudna, showed that it could be used to cut any piece of DNA very precisely and at specific sites.

It has been less than 10 years since its discovery but CRISPR has already had a huge impact on biomedical science and is the basis of new treatments being developed and tested in clinical trials for many diseases including cancer and blinding eye diseases. For example, a CRISPR-based treatment is being tested in a clinical trial for Leber congenital amaurosis (LCA), an inherited retinal disease (IRD) that causes sever vision loss at birth. There are other potential treatments in development for IRDs and other eye diseases such as glaucoma as the study below explains.

Featured Posts

Applications for the 2023 Transitions Change Agent Program Now Open Through December 31, 2022

Become a Change Agent and make a difference with your peers and patients!

Learn More

Swarovski and EssilorLuxottica Announce Ten-year Licensing Agreement

Swarovski and EssilorLuxottica announce that they have signed an exclusive license agreement for the design, manufacture and worldwide distribution of Swarovski Eyewear.

Read more

Industry Professionals and Trainers Joined Transitions Optical for “The Studio” Educational Event, 2nd Edition

Transitions Optical gathered over 80 industry professionals for a one-of-a-kind learning train the trainer event—Transitions® The Studio—on November 8, 2022.

Read more

Bausch + Lomb Launches Biotrue® Advanced Multi-Purpose Solution in Canada

New Formula Provides More Moisture on Contact Lenses

Read more

SILMO Istanbul 2022: A Record Attendance

SILMO ISTANBUL welcomed both local manufacturers and a number of international companies of the optical and eyewear industry.

Read more

Applications for the 2023 Transitions Change Agent Program Now Open Through December 31, 2022

Become a Change Agent and make a difference with your peers and patients!

Learn More

Swarovski and EssilorLuxottica Announce Ten-year Licensing Agreement

Swarovski and EssilorLuxottica announce that they have signed an exclusive license agreement for the design, manufacture and worldwide distribution of Swarovski Eyewear.

Read More

Industry Professionals and Trainers Joined Transitions Optical for “The Studio” Educational Event, 2nd Edition

Transitions Optical gathered over 80 industry professionals for a one-of-a-kind learning train the trainer event—Transitions® The Studio—on November 8, 2022.

Read More

Bausch + Lomb Launches Biotrue® Advanced Multi-Purpose Solution in Canada

New Formula Provides More Moisture on Contact Lenses

Read More

SILMO Istanbul 2022: A Record Attendance

SILMO ISTANBUL welcomed both local manufacturers and a number of international companies of the optical and eyewear industry.

Read More

Applications for the 2023 Transitions Change Agent Program Now Open Through December 31, 2022

Become a Change Agent and make a difference with your peers and patients!

Learn More

Swarovski and EssilorLuxottica Announce Ten-year Licensing Agreement

Swarovski and EssilorLuxottica announce that they have signed an exclusive license agreement for the design, manufacture and worldwide distribution of Swarovski Eyewear.

Read more

Industry Professionals and Trainers Joined Transitions Optical for “The Studio” Educational Event, 2nd Edition

Transitions Optical gathered over 80 industry professionals for a one-of-a-kind learning train the trainer event—Transitions® The Studio—on November 8, 2022.

Read more

Bausch + Lomb Launches Biotrue® Advanced Multi-Purpose Solution in Canada

New Formula Provides More Moisture on Contact Lenses

Read more

SILMO Istanbul 2022: A Record Attendance

SILMO ISTANBUL welcomed both local manufacturers and a number of international companies of the optical and eyewear industry.

Read more

Applications for the 2023 Transitions Change Agent Program Now Open Through December 31, 2022

Become a Change Agent and make a difference with your peers and patients!

Learn More

Swarovski and EssilorLuxottica Announce Ten-year Licensing Agreement

Swarovski and EssilorLuxottica announce that they have signed an exclusive license agreement for the design, manufacture and worldwide distribution of Swarovski Eyewear.

Read more

Industry Professionals and Trainers Joined Transitions Optical for “The Studio” Educational Event, 2nd Edition

Transitions Optical gathered over 80 industry professionals for a one-of-a-kind learning train the trainer event—Transitions® The Studio—on November 8, 2022.

Read more

Bausch + Lomb Launches Biotrue® Advanced Multi-Purpose Solution in Canada

New Formula Provides More Moisture on Contact Lenses

Read more

SILMO Istanbul 2022: A Record Attendance

SILMO ISTANBUL welcomed both local manufacturers and a number of international companies of the optical and eyewear industry.

Read more